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The main limitation of this study was that the findings were obtained using a retrospective study design and a small sample size. To evaluate the relationship between the development of CNV per se and the LC type, it is necessary to collect data from more patients with myopic CNV per se. In addition, the growth of CNV was not examined in the present study; it is necessary to evaluate its growth in the future. Moreover, OCTA may offer the advantage of noninvasively evaluating choroidal flow and vascularization. In this study, we investigated the relationship between choroidal vascularity and LCs. The results showed that LCs were observed in 22 eyes and CNV was located in the area surrounded by LC crack fragments in all eyes. We believe that the results from this study are informative for the management of myopic CNV per se.
Representative cases 1, 2, and 3 of myopic CNV associated with linear-type LC are shown in Figure 4. Case 1 showed LC progression and the development of CNV. It was the first case of CNV per se with LC progression. The inner site of CNV corresponded with LC progression. Case 2 showed LC recession and development of CNV. The location of CNV was consistent with the location of LC progression. It was the second case of CNV per se with LC progression. On FA, dot-shaped LCs were observed for 13 years. Although the patient had not received anti-vascular endothelial growth factor therapy, the development of CNV was associated with the enlargement of LCs. Case 3 showed regression of CNV at the site of LC progression. It was the third case of CNV per se with LC progression. The location of CNV did not agree with LC progression. 827ec27edc